Celeste Martin13 July 2024 | 8:20

Breakthrough HIV drug trial to 'revolutionise how infection is prevented'

An injection given twice a year has shown to be 100% effective against infection.

Breakthrough HIV drug trial to 'revolutionise how infection is prevented'

HIV / Pexels: Miguel Á. Padriñán

Gugs Mhlungu spoke to resident GP and Proactive Health Solutions CEO, Dr Fundile Nyati. 

Listen to their conversation in the audio clip below.

"It was a study done among young women between the ages of 16 and 25 - the people who are at a very high risk."
- Dr Fundile Nyati, GP and Proactive Health Solutions CEO

The trial, which took place at three sites in Uganda and 25 sites in South Africa, had 5 000 participants.

The principal investigator for the South African part of the study, Dr Linda-Gail Bekker, explains in the article that the trial tested whether the six-month injection of lenacapavir would provide better protection against HIV infection than two other drugs, both daily pills.

All three medications are pre-exposure prophylaxis (or PrEP) drugs.

"The current methods, whilst they work, there are certain challenges with them."
- Dr Fundile Nyati, GP and Proactive Health Solutions CEO
"It's definitely going to revolutionise how HIV is being prevented."
- Dr Fundile Nyati, GP and Proactive Health Solutions CEO
"The manufacturers are looking at going to the WHO and other bodies to get approval so that this can be made to benefit people on the ground."  
- Dr Fundile Nyati, GP and Proactive Health Solutions CEO

In the last year, there were 1,3 million new infections of HIV globally.


Scroll up to listen to the full interview.