#RWC2015: Jan Serfontein to replace de Villiers in the squad
An announcement on the captaincy for the match against Scotland will be made on Wednesday.
The Springbok captain fractured his jaw during yesterday's win over Samoa.
De Villiers took a heavy blow to the right side of his jaw during the 72 minutes of yesterday's game against Samoa.
X-rays and scans confirm that his jaw was indeed fractured.
It brings to an end a heroic story of perseverance after de Villiers recovered from a serious knee injury and another broken jaw injury just to make it to the world cup.
Coach Heyneke Meyer has described the loss as heartbreaking, calling de Villiers the glue that keeps the team together.
DE VILLIERS NO STRANGER TO WORLD CUP INJURIES
The 34-year-old Paarl Gymnasium alumnus' Springbok career has been riddled with injury, but it's been the quadrennial Rugby World Cup that has been most unkind to de Villiers.
De Villiers has been selected for four World Cups, and at each one he suffered an injury.
He made his first senior-level appearance for South Africa in November 2002 against France, but suffered a major knee injury five minutes into the game.
The veteran centre would go on to miss the 2003 World Cup in Australia as a result. The 2007 tournament, which the Springboks won in France was no different for him.
He won the World Cup with South Africa, although he tore his biceps during the opening game of the tournament and took no further part.
Four years later at the 2011 World Cup in New Zealand, injury was once again waiting for him. In New Zealand he played just 25 minutes in the first game against Wales when he popped a rib.
He recovered and played the last Pool B game from the bench against Samoa. It was still to be a bad ending for him as the Boks crashed to defeat against Australia in the quarter final.
His provincial and Super Rugby career at Western Province and the Stormers wasn't sparred either, missing large chunks of the 2015 season and previous years with various injuries, including a troublesome wrist niggle.
An announcement on the Springboks captaincy for the match against Scotland on 3 October will be made on Wednesday.
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