The Blitzboks carried on their Saturday form on Sunday in Port Elizabeth.
Several thugs forced Hannes Strydom off the road in Waterkloof by smashing a brick through his car window.
Team doctor Craig Roberts said Jean de Villiers will likely be out of action for at least 8 months.
Extent of de Villiers knee injury still unknown
The Springbok scrum-half is the third South African to win the award after Jaque Fourie.
The win marks the first time the Welsh have beaten South Africa since 1999.