Lionel Messi set a La Liga record of 253 goals with a hat-trick in Barcelona's 5-1 rout of Sevilla.
In the big games, Portugal beat Argentina, England beat Scotland and Germany beat Spain.
It was goals galore on Friday as European teams battled in the qualifying rounds for the Euro 2016.
Notable absentees include US goalkeeper Tim Howard and Costa Rica stopper Keylor Navas.
Real Madrid showed their superiority in their first-ever win over Liverpool in the Uefa Champions League.
A single goal from John O’Shea in the dying minutes of the game saw Ireland draw with Germany 1-1.